This unusual and interesting name is of English loctional origin, from either of the places called "Muston" in Leicestershire and East Yorkshire. That in Leicestershire is first recorded as "Moston" in 1125 and "Muston" in 1333 and means either an enclosure by a muddy stream, from the Old English pre 7th Century "must" or an enclosure, homestead or village infested by mice, from the Old English "Mus-tun". The placename in East Yorkshire is first recorded as "Mustone" in the Domesday Book of 1086 and as "Mussetuna" in 1170 and means "Musi's tun", with the Old Norse byname "Musi" as the first element. The Old English "tun" meant "enclosure or homestead and later village, eventually "town". In the modern idiom, the surname can be found as "Mustin", "Muston" and "Mustyn". The first recorded spelling of the family name is shown to be that of George Mustine, christened. which was dated 5th July 1637, St. Andrews, Holborn, London. during the reign of King Charles I, The Martyr, 1625 - 1649. Surnames became necessary when governments introduced personal taxation. In England this was known as Poll Tax. Throughout the centuries, surnames in every country have continued to "develop" often leading to astonishing variants of the original spelling.

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